Arizona Cardinals Vs. Kansas City Chiefs Odds: NFL Preseason Week 2

The Arizona Cardinals are at home again for their second preseason game and this time they take on Patrick Mahomes and the Kansas City Chiefs.

The Chiefs are coming off back to back Super Bowl appearances and are the favorites to win the game. (And Super Bowl LVI)

FanDuel Game Odds

Spread: KC -3 (-115) / ARI: +3 (-105)

Moneyline: KC -160 / ARI +135 

Cardinals and Chiefs Game Preview

We aren’t exactly sure who will suit up for the Arizona Cardinals, but you can expect Kansas City starters to play most of the first half. Kanas City Chiefs’ head coach Andy Reid told the media that his starters will most likely play the first half of the game, with his second and third-string players finishing out the second half of the game. This means Mahomes, Travis Kelce, and Tyreek Hill are expected to take the field for the Chiefs’ offense. And for their defense, we will see Tyrann Mathieu and Chris Jones in the first half.

As for the Arizona Cardinals, they looked good in their first preseason game with a win over the Dallas Cowboys. Kyler Murray, Deandre Hopkins, and J.J. Watt didn’t play, but we were able to see first round draft pick Zaven Collins work his magic on defense. 

Things will be a little different in the game against the Chiefs, as Murray is expected to play some snaps on Friday. Watt is likely to sit out again, but he ensures fans that he will be ready to go for the season opener on September 12 against the Tennessee Titans. 

Running backs Eno Benjamin and Chase Edmonds are expected to get plenty of snaps as they fight for a top spot on the team. We can also expect kicker Matt Prater to get plenty of chances to score points after kicking the game winning field goal last week.  

Cardinals and Chiefs Sports Betting Odds

The Arizona Cardinals are shaping up to be a decent team this year, but they are in one of the hardest divisions in the league, making it even tougher for them to land a playoff spot. In fact, BetMGM has the Cardinals at +165 to make the playoffs and FanDuel has the Cardinals at +4800 to win the Super Bowl.

Most sportsbook apps have the Kansas City Chiefs as the favorite to win the Super Bowl this year, which would make it the team’s third straight Super Bowl appearance. BetMGM has the Chiefs at -1000 to make the playoffs this year and FanDuel has them at +500 to win the Super Bowl.

Both quarterbacks are in the talks to win MVP. BetMGM has Mahomes at +600 to win MVP and Murray at +2500.

How To Watch/Listen To The Cardinals NFL Preseason Week 2 Game

  • Date: Friday, August 20
  • Time: 7:00 PM MST
  • Location: State Farm Stadium in Glendale, AZ
  • TV: ESPN
About the Author

Calli Varner

Calli is the editor and senior contributor of As a football fanatic and lifelong resident of Arizona, she proudly cheers on the Arizona Cardinals. But her heart belongs to her number one team, the Kansas City Chiefs. (Go Chiefs Kingdom!) You can follow Calli on Twitter at @CalliDoesSports.